Built by scientists and clinicians from
What is anexposome?
A person's accumulated external exposures, from conception onwards.1
70% of chronic disease risk is driven by everyday exposures like cosmetics, stress, infections and pollution.2 An EXPIN test identifies the ones most important to you and your disease.
Read the scienceHow it works
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Step 1:Tell us your whole story.
Complete an adaptive questionnaire that takes a deep dive into your medical and exposure history.
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Step 2:Show us your cabinets.
Take photos of the products you use every day, from supplements and medication to cosmetics and cleaning sprays.
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Step 3:We map your exposome.
We check your story against the published research on Hashimoto's and rank what we find.
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Step 4:Review Results with a Provider or Coach.
Work with your physician, health coach, or other practitioner to understand your results and plan next actions.
Your Expotype Report.
The EXPIN test analyzes thousands of potential relationships between your exposure and health outcomes.
It cross-references these against trusted biomedical evidence and evaluates the most relevant exposures as well as those which can be ruled out.
EXPIN can help you:
- Research the root causes behind your disease
- Walk into doctor's appointments more knowledgeable
- Find new directions for testing and treatment
Encrypted, never sold.
Natalie
Female · born March 8, 1994 · updated October 12, 2026
What we checked
- published findings
- 611
- exposures screened
- 79
- deemed relevant
- 3
- highly relevant
- 1
Your health state
- Reported conditions
- Hashimoto's disease
- Reported symptoms
- elevated thyroid antibodiesconstant fatigue
High relevance
Phthalates (DEP)
From your cabinet: Hairspray
Diethyl phthalate (DEP) is commonly used in cosmetic products to make scents last longer. DEP is easily inhaled, ingested, or absorbed through skin contact. Phthalates have been linked to endocrine disruption and are associated with altered thyroid hormone levels. The ingredients list on your hairspray includes it, which makes the hairspray a likely source of your exposure and one worth raising with your doctor. Phthalates are processed and cleared rapidly through urine, so changing products can lower your exposure quickly.
What the research says · 3 studies
Moderate relevance
SARS-CoV-2 and COVID-19
COVID-19 infection has been linked to significantly elevated risk of new thyroid disease, including hypothyroidism, in the years following illness, and SARS-CoV-2 has been found to directly infect thyroid tissue. Given that you already have Hashimoto's disease and reported losing your appetite for several months after your first COVID infection in early 2020, that illness could be a contributor to ongoing thyroid disruption worth discussing with your doctor.
See what EXPIN members have to say.
Genetics alone didn't answer everything for me: it couldn't explain why I got sick and my sisters didn't… EXPIN helped identify some really unexpected personal exposures, grounded in both scientific information and relevance to my life.
I appreciate that EXPIN brings together the different pieces of your life, using questions not normally asked by your doctor, and connects those pieces with scientific evidence to paint a picture of your disease origin and triggers, in a simple and straightforward way.
I've spent the last 20 years wanting to understand my health. I get bloodwork twice a year, I have had rounds of genetic testing to learn what my children and I might be predisposed to. But my genes and my labs were only ever telling me part of the story… Then I found EXPIN, and it felt like finding the missing piece.
EXPIN is able to tell me which exposures I actually need to think through, and which I don't need to worry about at all. There is true relief in that: being told, with evidence, where to focus and where to let go.
Built by scientists, not internet personalities.
Our scientists and clinicians work in environmental health, diagnostics and biophysics.
Uta Guo
MD, MBA
Family physician
Quinto Gesiotto
MD, MS
Hematologist and medical oncologist
Leonardo Trasande
MD, MPP
Environmental health and pediatric epidemiology
Kuljeet Rai
MD
Precision care and clinical investigation
Richard Goldstein
MD, PhD, MHCM
Endocrine surgeon and clinical investigator
Krisna Bhargava
PhD
Scientist and inventor
Jonathan Freedman
PhD
Toxicologist
Robert (Bob) Molinari
PhD, MBA
Biotechnology strategy
Frequently Asked Questions
Patients who have been struggling with a chronic disease, like an autoimmune disease, and are interested in looking at root causes in their environment and lifestyle behaviors. There are thousands of potential links between exposures and disease. EXPIN helps uncover the few that are most important for you, giving you a basis for action or peace of mind.
EXPIN does not require that you give blood, urine, or another biological sample. It is a digital service that comprehensively profiles your health and exposure history and evaluates potential links against trusted biomedical evidence. It can be used in tandem with laboratory tests, such as in a functional care setting.
EXPIN does not sell treatments, supplements, or protocols. It tells you which exposures the scientific research ties to your disease, how well each one fits your history, and which studies say so. What to do next stays between you and your doctor, whichever kind of doctor that is.
EXPIN can be purchased directly by patients or by providers on behalf of their patients. We highly recommend that patients work with a healthcare provider or integrative health coach experienced with evidence-based techniques and root-cause-oriented care. Your results may point to new diagnostic, treatment, or exposure-related steps. Many of these require oversight from a licensed healthcare provider.
Yes. You can sign up for EXPIN as a "delegate" and complete the onboarding on behalf of your loved one.
All data added to EXPIN is encrypted in transit and at rest and protected with security practices aligned to healthcare-industry standards. We never sell your health information or use it for advertising.
Currently, EXPIN supports Hashimoto's disease and hypothyroidism. We are adding more conditions regularly.
Uncover the root cause in your environment.
EXPIN is best done when you are at home and have 1-2 hours to spare.